- Dr. Cristina Vassalle, PhD
- Fondazione CNR-Regione Toscana G. Monasterio, Pisa, Italy.
- Dr. Laura Sabatino, PhD
- Istituto di Fisiologia Clinica del CNR, Pisa, Italy.
Special Issue Introduction
Oxidative stress and inflammation are interconnected critical determinants of cardiovascular risk and disease, and possible target of interventional strategies for the prevention of redox/inflammation-related biological consequences.
Therefore, further researches on the evaluation of oxidative stress and inflammation pathways are required to better understand cardiovascular physiopathology. Moreover, it would be important to identify significant biological markers of oxidative stress and inflammation, potentially useful in the clinical practice in the future, and to assess the role of a healthy life-style to prevent cardiovascular onset and development.
As there are many issues still under discussion in this field, we invite different researchers to contribute original research as well as review articles in the field of:
* Oxidative stress, inflammation and cardiovascular risk factors (e.g. hypertension, menopause, diabetes, smoking habit and dyslipidemia);
* Roles of oxidative stress and/or inflammation in onset and development of atherosclerotic plaque;
* Mitochondrial functions and redox biology;
* Cellular and molecular mechanisms underlying the crosstalk between oxidative stress and inflammation in cardiovascular biology;
* Laboratory biomarkers and physiological tests to assess oxidative stress status and inflammatory processes;
* Life-style, oxidative stress and inflammation;
* Dietary/supplemental antioxidant and drugs with antioxidant/antiinflammatory properties;
* Exercise training and hormesis as adaptive response to oxidative stress;
* Genetic susceptibility to cardiovascular disease related to differences in oxidative stress and inflammation: significance of the inter-individual variability in the cardiovascular risk assesment;
* Omic technologies to assess oxidative stress and inflammation: promises and difficulties to overcome;
* Oxidative stress-related microRNA: an hope for the future?
* The redox basis of epigenetic modifications: a glance on their role and functions.
KeywordsOxidative stress, inflammation, cardiovascular physiopathology, biological markers, prevention, laboratory biomarkers, life-style, omic technologies, mitochondrial function
Submission Deadline30 Jun 2020