fig2

Stem cell-based therapy for myopic maculopathy: a new concept

Figure 2. The characteristic alternations of each category based on META-PM classification. The thickness of retina, choroid, and sclera are decreasing along with a higher grade of myopic maculopathy. Tessellated fundus is characterized by hypoplasia of the RPE, reduced filling of the choriocapillaris, and increased pigmentation of the choroidal stroma. Diffuse chorioretinal atrophy is characterized by a marked reduction of all layers of choroidal vessels. In the diffuse chorioretinal atrophy stage, the outer retina and RPE are present even though the choroid is absent. Patchy chorioretinal atrophy is characterized by the absence of the outer retina layers, RPE, and all layers of the choroidal vessels. The inner retina directly touches the sclera. The Bruch’s membrane is no longer intact. The structural alternations of macular atrophy are the same as those of patchy chorioretinal atrophy. RPE: retinal pigment epithelium; BM: Bruch’s membrane.

Journal of Translational Genetics and Genomics
ISSN 2578-5281 (Online)
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