fig2

Figure 2. Management of DOACs in relation to surgery timing (modified from^[19]). *Andexanet alfa must be administered as a bolus of 30 mg/min in 15 min (low dose) or 30 min (high dose), followed by i.v. infusion of 4 mg (low dose) or 8 mg (high dose) per min for 120 min. DOACs: direct oral anticoagulants.