fig1

Figure 1. A patient with wake-up onset stroke. Non-contrast CT excluded hemorrhage and indicated subtle loss of grey-white differentiation in the left insular region (A); CT perfusion time to maximum (Tmax) map showing delayed flow via collaterals in the left middle cerebral artery territory confirmed the diagnosis of ischemic stroke (B); Automated segmentation of CT perfusion cerebral blood flow < 30% of normal brain (36 mL magenta region estimated as irreversibly injured ischemic core) (C) and Tmax > 6-s delay (124 mL green region estimated tissue at risk) from RAPID software (D); CT angiography demonstrating distal M1 middle cerebral artery occlusion (E) 24-h diffusion MRI after successful endovascular thrombectomy showing no interval growth in ischemic core (F)