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From: Deletion of retinoic acid-related orphan receptor gamma reduces body weight and hepatic lipids in mice by modulating the expression of lipid metabolism genes

Deletion of retinoic acid-related orphan receptor gamma reduces body weight and hepatic lipids in mice by modulating the expression of lipid metabolism genes

Figure 2. RORγ gene deletion reduces hepatic lipids and increases plasma triglycerides. Lipids from WT and KO mice livers (n = 3) were extracted by Bligh and Dyer method to measure cholesterol (A) and triglycerides (B). Total cholesterol (C) and triglycerides (D) were also measured in the plasma of these mice. Values were plotted as mean ± SD. P values were calculated using two-tailed Student’s t test. **P < 0.01. WT: wild type; KO: knockout; RORγ: retinoic acid-related orphan receptor γ