fig1

Figure 1. Principal transcriptional regulators of M1 and M2 activation of macrophages and mechanisms of their stimulation/inhibition. GM-CSF: granulocyte-macrophage colony-stimulating factor; M-CSF: macrophage colony-stimulating factor; IFN-γ: interferon γ; LPS: lipopolysaccharide; IL: interleukin; IC: interferon consensus; TNF-α: tumor necrosis factor α; TGF-β: transforming growth factor β; CCL18: chemokine CC-motif ligand 18