fig1

Figure 1. The effect of insulin and glucose on the regulation of gene expression^[9]. IRS1/IRS2: insulin receptor substrates 1 and 2; Akt1: proteinase B; PI3K: phosphatidylinositol-3-kinase; SREBP-1c: sterol-regulated element-binding protein 1C; FAS: fatty acid synthase; FOXO: transcription factors; Glut4: glucose transporter; GK: glucokinase; L-PK: liver pyruvate kinase; S14: spot 14; G6P: glucose-6-phosphate