Vessel Plus 2021;5:[Accepted].10.20517/2574-1209.2021.41@The Author(s) 2021
Ear, nose and throat in ANCA-associated vasculitis: a comprehensive review
Correspondence Address: Dr. Roberto Padoan, Rheumatology Unit, University of Padova, Via Giustiniani, 2, 35128 Padova, Italy. E-mail: firstname.lastname@example.org
Received: 28 Feb 2021 | Revised: 1 May 2021 | Accepted: 21 May 2021 | First online: 24 May 2021
AbstractEar, nose and throat (ENT) involvement is a common feature in ANCA-associated vasculitis (AAV), particularly in granulomatosis with polyangiitis (GPA) and eosinophilic granulomatosis with polyangiitis (EGPA). Over the last decade, substantial advance has been made in understanding AAV pathogenesis, classification, and treatment. Typical ENT symptoms may include sinonasal, otologic, pharyngeal, and laryngeal manifestations. The otolaryngologic symptoms of AAV sometimes might be misdiagnosed in aetiology as infectious or allergic. Thus, rapid recognition and early diagnosis of AAV as the cause of the symptoms prevent the risk of irreversible organ damage. The high impact of ENT symptoms on quality of life of AAV patients confirms the importance of their early treatment through specific local and systemic approach. Appropriate interdisciplinary management to early recognition of AAV and initiation of treatment may reduce morbidity in these patients. The purpose of this comprehensive review is to describe the clinical, histologic and radiological findings of ENT involvement in AAV, and to update their surgical and therapeutic management, with a focus also on the role of a multidisciplinary team, involving the otorhinolaryngologist.
KeywordsAntineutrophil cytoplasmic antibody, ANCA associated vasculitis, granulomatosis with polyangiitis, microscopic polyangiits, eosinophilic granulomatosis with polyangiitis, ear nose and throat
Cite This Article
Padoan R, Campaniello D, Felicetti M, Cazzador D, Schiavon F. Ear, nose and throat in ANCA-associated vasculitis: a comprehensive review. Vessel Plus 2021;5:[Accept]. http://dx.doi.org/10.20517/2574-1209.2021.41