Topic: Vascular Remodeling 2018: the Updates

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A special issue of Vessel Plus (Online ISSN:2574-1209).

Deadline for manuscript submissions: 8 Jun 2018

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Guest Editor(s)

  • Prof. Alexander D. Verin, PhD
    Professor, Medical College of Georgia at Augusta University, Vascular Biology Center and Pulmonary Medicine, Augusta, GA, USA.

    Website | E-mail

  • Dr. Evgenia V. Gerasimovskaya, PhD
    Associate Professor, University of Colorado Denver, Pediatric Critical Care Medicine, Aurora, CO, USA.

    Website | E-mail

Special Issue Introduction:

The field of vascular remodeling is fundamental to cardiovascular research, as vessel growth, differentiation, development and regression are involved in numerous physiologic and pathologic conditions of both systemic and pulmonary circulation. We are very enthusiastic to conduct our research on pulmonary artery microvascular and vasa vasorum endothelial cells that are extremely and uniquely sensitive to pathologic conditions and environmental factors that control these vessel phenotype and function. We realize that there is a need in the updates on the fundamental and generalized knowledge that would integrate research data and the ideas from another type of blood vessels throughout the body. We are inspired by the opportunity to overview and bring together the results from recent findings in the field of vascular remodeling.


Vascular development; vasculogenesis, angiogenesis and arteriogenesis; pathologic and physiologic vessel growth; vascular permeability; bioengineering; signaling, metabolic, and epigenetic signatures of arteries, veins and capillaries

Submission Information:

Articles of special issue are free of charge for article processing.
For Author Instructions, please refer to
For Online Submission, please login at
Submission Deadline: 8 Jun 2018
Contacts: Sylvia Wang, Managing Editor,

Published Articles Download All Articles
  • Thrombospondins and remodeling of the tumor microenvironment

    Olga Stenina-Adognravi , Santoshi Muppala , Jasmine Gajeton
    Vascular remodeling defines cancer growth and aggressiveness. Although cancer cells produce pro-angiogenic signals, the fate of angiogenesis critically depends on the cancer microenvironment. Composition of the extracellular matrix (ECM) and tumor inflammation determine whether a cancer will remain dormant, will be recognized by the immune system and eliminated, or whether the tumor will... Read more
    This article belongs to the Special Issue Vascular Remodeling 2018: the Updates
    Vessel Plus 2018;2:30. | doi:10.20517/2574-1209.2018.40
    Published on: 10 Oct 2018  | Viewed:147  | Downloaded:4
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  • A current view of G protein-coupled receptor - mediated signaling in pulmonary hypertension: finding opportunities for therapeutic intervention

    Derek Strassheim , Vijaya Karoor , Kurt Stenmark , Alexander Verin , Evgenia Gerasimovskaya
    Pathological vascular remodeling is observed in various cardiovascular diseases including pulmonary hypertension (PH), a disease of unknown etiology that has been characterized by pulmonary artery vasoconstriction, right ventricular hypertrophy, vascular inflammation, and abnormal angiogenesis in pulmonary circulation. G protein-coupled receptors (GPCRs) are the largest family in the genome and... Read more
    This article belongs to the Special Issue Vascular Remodeling 2018: the Updates
    Vessel Plus 2018;2:29. | doi:10.20517/2574-1209.2018.44
    Published on: 30 Sep 2018  | Viewed:427  | Downloaded:29
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  • Fetal programming and its effects on vascular pulmonary circulation

    Carmela Rita Balistreri
    Into the scientific community, consensus about the emerging concept of “the fetal origin of adult diseases” is growing. It sustains that the parental (of the two parents) adversities, and the related external influences, during the intra-utero/perinatal life of each eutherian mammal organism, human included, can permanently set the structure and functionality of specific body systems (i.e.,... Read more
    This article belongs to the Special Issue Vascular Remodeling 2018: the Updates
    Vessel Plus 2018;2:25. | doi:10.20517/2574-1209.2018.35
    Published on: 19 Sep 2018  | Viewed:196  | Downloaded:8
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  • Immunohistochemistry of the circadian clock in mouse and human vascular tissues

    Ciprian B. Anea , Ana M. Merloiu , David J. R. Fulton , Vijay Patel , R. Dan Rudic
    Aim: The circadian clock is a molecular network that controls the body physiological rhythms. In blood vessels, the circadian clock components modulate vascular remodeling, blood pressure, and signaling. The goal in this study was to determine the pattern of expression of circadian clock proteins in the endothelium, smooth muscle, and adventitia of the vasculature of human and mouse tissues.... Read more
    This article belongs to the Special Issue Vascular Remodeling 2018: the Updates
    Vessel Plus 2018;2:16. | doi:10.20517/2574-1209.2018.46
    Published on: 20 Jul 2018  | Viewed:607  | Downloaded:44
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  • Histone deacetylases in vascular permeability and remodeling associated with acute lung injury

    Laszlo Kovacs , Anita Kovacs-Kasa , Alexander D. Verin , David Fulton , Rudolf Lucas , Yunchao Su
    Acute lung injury (ALI) is a severe progressive disorder that arises from a wide range of causes such as toxins or inflammation, resulting in significant morbidity and mortality. There are no effective therapeutic options apart from mechanical ventilation strategies. While the mechanisms that govern the clinically relevant process of increased endothelial cell (EC) permeability and remodeling... Read more
    This article belongs to the Special Issue Vascular Remodeling 2018: the Updates
    Vessel Plus 2018;2:15. | doi:10.20517/2574-1209.2018.06
    Published on: 10 Jul 2018  | Viewed:409  | Downloaded:20
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Vessel Plus ISSN 2574-1209 (Online)
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