fig2

Perivascular mast cells promote neointimal elastin deposition and suppress chronic vein graft restenosis in hyperlipidaemic mice

Figure 2. Mast cell deficiency in hyperlipidaemic mice increased neointima area with elevated chronic cell proliferation. (A) Representative images of cell proliferation in 4-week-old vein grafts. Proliferating cells were labelled using an antibody against Ki67 (green) and cell nuclei by DAPI (blue). The neointimal area in apoE-/- KitW-sh/W-sh vein grafts was significantly higher than all other groups (B), associated with elevated cell proliferation by 4 weeks (C). n > 6 for all groups; **P < 0.01 by one-way analysis of variance plus Tukey post hoc test

Vessel Plus
ISSN 2574-1209 (Online)
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